Assessment of Structural Intolerance and Durability
General Structure Information 4hw5 C3 crystal structure of the human c3a anaphylatoxin 2.25Å AUTH G.BAJIC,L.YATIME,A.KLOS,G.R.ANDERSENTITL HUMAN C3A AND C3A DESARG ANAPHYLATOXINS HAVE CONSERVEDTITL 2 STRUCTURES, IN CONTRAST TO C5A AND C5A DESARG.REF PROTEIN SCI. V. 22 204 2013REFN ISSN 0961-8368PMID 23184394DOI 10.1002/PRO.2200 Variant Set Distributions Mapped Variants
General Structure Information 2xrc CFI human complement factor i 2.69Å AUTH P.ROVERSI,S.JOHNSON,J.J.CAESAR,F.MCLEAN,K.J.LEATH,AUTH 2 S.A.TSIFTSOGLOU,B.P.MORGAN,C.L.HARRIS,R.B.SIM,S.M.LEATITL STRUCTURAL BASIS FOR COMPLEMENT FACTOR I CONTROL AND ITSTITL 2 DISEASE-ASSOCIATED SEQUENCE POLYMORPHISMS.REF PROC.NATL.ACAD.SCI.USA V. 108 12839 2011REFN ISSN 0027-8424PMID 21768352DOI 10.1073/PNAS.1102167108 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants