Assessment of Structural Intolerance and Durability
General Structure Information 3f7p ITGB4 crystal structure of a complex between integrin beta4 and plectin 2.75Å AUTH J.M.DE PEREDA,M.P.LILLO,A.SONNENBERGTITL STRUCTURAL BASIS OF THE INTERACTION BETWEENTITL 2 INTEGRIN ALPHA6BETA4 AND PLECTIN AT THETITL 3 HEMIDESMOSOMESREF EMBO J. V. 28 1180 2009REFN ISSN 0261-4189PMID 19242489DOI 10.1038/EMBOJ.2009.48 Variant Set Distributions Mapped Variants
General Structure Information 2aze RB1 structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer 2.55Å AUTH S.M.RUBIN,A.L.GALL,N.ZHENG,N.P.PAVLETICHTITL STRUCTURE OF THE RB C-TERMINAL DOMAIN BOUND TOTITL 2 E2F1-DP1: A MECHANISM FOR PHOSPHORYLATION-INDUCEDTITL 3 E2F RELEASE.REF CELL(CAMBRIDGE,MASS.) V. 123 1093 2005REFN ISSN 0092-8674PMID 16360038DOI 10.1016/J.CELL.2005.09.044 Variant Set Distributions Mapped Variants
General Structure Information 2rol CD3E structural basis of pxxdy motif recognition in sh3 binding -1.0Å AUTH O.AITIO,M.HELLMAN,T.KESTI,I.KLEINO,O.SAMUILOVA,AUTH 2 K.PAAKKONEN,H.TOSSAVAINEN,K.SAKSELA,P.PERMITITL STRUCTURAL BASIS OF PXXDY MOTIF RECOGNITION IN SH3TITL 2 BINDINGREF J.MOL.BIOL. V. 382 167 2008REFN ISSN 0022-2836PMID 18644376DOI 10.1016/J.JMB.2008.07.008 Variant Set Distributions Mapped Variants
General Structure Information 3klt VIM crystal structure of a vimentin fragment 2.7Å AUTH S.NICOLET,H.HERRMANN,U.AEBI,S.V.STRELKOVTITL ATOMIC STRUCTURE OF VIMENTIN COIL 2.REF J.STRUCT.BIOL. V. 170 369 2010REFN ISSN 1047-8477PMID 20176112DOI 10.1016/J.JSB.2010.02.012 Variant Set Distributions Mapped Variants
General Structure Information 3kci HERC2 the third rld domain of herc2 1.8Å AUTH J.R.WALKER,L.QIU,A.VESTERBERG,J.WEIGELT,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL STRUCTURE OF THE THIRD RLD DOMAIN OF HERC2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3lrq TRIM37 crystal structure of the u-box domain of human ubiquitin- protein ligase (e3), northeast structural genomics consortium target hr4604d. 2.29Å AUTH A.KUZIN,Y.CHEN,J.SEETHARAMAN,M.MAO,R.XIAO,AUTH 2 C.CICCOSANTI,R.SHASTRY,J.K.EVERETT,R.NAIR,AUTH 3 T.B.ACTON,B.ROST,G.T.MONTELIONE,L.TONG,J.F.HUNTTITL E3 UBIQUITIN-PROTEIN LIGASE RING DOMAIN FROM HUMANTITL 2 TRIPARTITE MOTIF-CONTAINING PROTEIN 37 (TRIM37),TITL 3 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGETTITL 4 HR4604D.REF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2gd7 HEXIM1 the structure of the cyclin t-binding domain of hexim1 reveals the molecular basis for regulation of transcription elongation -1.0Å AUTH S.A.DAMES,A.SCHONICHEN,A.SCHULTE,M.BARBORIC,AUTH 2 B.M.PETERLIN,S.GRZESIEK,M.GEYERTITL STRUCTURE OF THE CYCLIN T BINDING DOMAIN OF HEXIM1TITL 2 AND MOLECULAR BASIS FOR ITS RECOGNITION OF P-TEFB.REF PROC.NATL.ACAD.SCI.USA V. 104 14312 2007REFN ISSN 0027-8424PMID 17724342DOI 10.1073/PNAS.0701848104 […]
General Structure Information 3ikk VAPB crystal structure analysis of msp domain 2.5Å AUTH J.SHI,S.LUA,J.S.TONG,J.SONGTITL ELIMINATION OF THE NATIVE STRUCTURE AND SOLUBILITY OF THETITL 2 HVAPB MSP DOMAIN BY THE PRO56SER MUTATION THAT CAUSESTITL 3 AMYOTROPHIC LATERAL SCLEROSIS.REF BIOCHEMISTRY V. 49 3887 2010REFN ISSN 0006-2960PMID 20377183DOI 10.1021/BI902057A Variant Set Distributions Mapped Variants
General Structure Information 2wvr GMNN human cdt1:geminin complex 3.3Å AUTH V.DE MARCO,P.J.GILLESPIE,A.LI,N.KARANTZELIS,AUTH 2 E.CHRISTODOULOU,R.KLOMPMAKER,S.VAN GERWEN,A.FISH,AUTH 3 M.V.PETOUKHOV,M.S.ILIOU,Z.LYGEROU,R.H.MEDEMA,AUTH 4 J.J.BLOW,D.I.SVERGUN,S.TARAVIRAS,A.PERRAKISTITL QUATERNARY STRUCTURE OF THE HUMAN CDT1-GEMININTITL 2 COMPLEX REGULATES DNA REPLICATION LICENSING.REF PROC.NATL.ACAD.SCI.USA V. 106 19807 2009REFN ISSN 0027-8424PMID 19906994DOI 10.1073/PNAS.0905281106 Variant Set Distributions Mapped Variants
General Structure Information 3hfh TCERG1 crystal structure of tandem ff domains 2.7Å AUTH M.LU,J.YANG,Z.REN,S.SABUI,A.ESPEJO,M.T.BEDFORD,AUTH 2 R.H.JACOBSON,D.JERUZALMI,J.S.MCMURRAY,X.CHENTITL CRYSTAL STRUCTURE OF THE THREE TANDEM FF DOMAINS OFTITL 2 THE TRANSCRIPTION ELONGATION REGULATOR CA150.REF J.MOL.BIOL. V. 393 397 2009REFN ISSN 0022-2836PMID 19660470DOI 10.1016/J.JMB.2009.07.086 Variant Set Distributions Mapped Variants