Assessment of Structural Intolerance and Durability
General Structure Information 2ds4 TRIM45 solution structure of the filamin domain from human tripartite motif protein 45 -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FILAMIN DOMAIN FROMTITL 2 HUMAN TRIPARTITE MOTIF PROTEIN 45REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mqm ASH1L crystal structure of the bromodomain of human ash1l 2.54Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 2cre CASS4 solution structure of rsgi ruh-036, an sh3 domain from human cdna -1.0Å AUTH A.Z.M.RUHUL MOMEN,H.HIROTA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-036, AN SH3 DOMAINTITL 2 FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2edj ROBO2 solution structure of the fifth ig-like domain from human roundabout homolog 2 -1.0Å AUTH C.KUROSAKI,K.IZUMI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAINTITL 2 FROM HUMAN ROUNDABOUT HOMOLOG 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yul SOX17 solution structure of the hmg box of human transcription factor sox-17 -1.0Å AUTH H.ABE,N.TOCHIO,K.MIYAMOTO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HMG BOX OF HUMANTITL 2 TRANSCRIPTION FACTOR SOX-17REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2epp PATZ1 solution structure of the first c2h2 type zinc finger domain of zinc finger protein 278 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 278REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2crf RANBP3 solution structure of the ran_bp1 domain of ran-binding protein-3 -1.0Å AUTH H.P.ZHANG,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RAN_BP1 DOMAIN OFTITL 2 RAN-BINDING PROTEIN-3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2r55 STARD5 human star-related lipid transfer protein 5 2.5Å AUTH A.G.THORSELL,W.H.LEE,C.PERSSON,M.I.SIPONEN,M.NILSSON,AUTH 2 R.D.BUSAM,T.KOTENYOVA,H.SCHULER,L.LEHTIOTITL COMPARATIVE STRUCTURAL ANALYSIS OF LIPID BINDING STARTTITL 2 DOMAINS.REF PLOS ONE V. 6 19521 2011REFN ESSN 1932-6203PMID 21738568DOI 10.1371/JOURNAL.PONE.0019521 Variant Set Distributions Mapped Variants
General Structure Information 2ebm RWDD1 solution structure of the rwd domain of human rwd domain containing protein 1 -1.0Å AUTH M.YONEYAMA,T.TOMIZAWA,S.KOSHIBA,S.WATABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 DOMAIN CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2dnn RBM12 solution structure of rna binding domain in rna-binding protein 12 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 RNA-BINDING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants