Assessment of Structural Intolerance and Durability
General Structure Information 3ltl ARFGEF1 crystal structure of human big1 sec7 domain 2.2Å AUTH J.C.ZEEH,P.C.SIMISTER,V.ROUSSEAU,A.JOUBERT,J.CHERFILS,V.BIOUTITL THE SEC7 DOMAIN STRUCTURES OF HUMAN BIG1 AND CYTOHESIN1 ARFTITL 2 NUCLEOTIDE EXCHANGE FACTORSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d86 VAV3 solution structure of the ch domain from human vav-3 protein -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMANTITL 2 VAV-3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2fp0 ADPRHL2 human adp-ribosylhydrolase 3 2.05Å AUTH C.MUELLER-DIECKMANN,S.KERNSTOCK,M.LISUREK,J.P.VON KRIES,AUTH 2 F.HAAG,M.S.WEISS,F.KOCH-NOLTETITL THE STRUCTURE OF HUMAN ADP-RIBOSYLHYDROLASE 3 (ARH3)TITL 2 PROVIDES INSIGHTS INTO THE REVERSIBILITY OF PROTEINTITL 3 ADP-RIBOSYLATION.REF PROC.NATL.ACAD.SCI.USA V. 103 15026 2006REFN ISSN 0027-8424PMID 17015823DOI 10.1073/PNAS.0606762103 Variant Set Distributions Mapped Variants
General Structure Information 3mvb MTERF crystal structure of a triple rfy mutant of human mterf1 bound to the termination sequence 2.79Å AUTH E.YAKUBOVSKAYA,E.MEJIA,J.BYRNES,E.HAMBARDJIEVA,AUTH 2 M.GARCIA-DIAZTITL HELIX UNWINDING AND BASE FLIPPING ENABLE HUMAN MTERF1 TOTITL 2 TERMINATE MITOCHONDRIAL TRANSCRIPTION.REF CELL(CAMBRIDGE,MASS.) V. 141 982 2010REFN ISSN 0092-8674PMID 20550934DOI 10.1016/J.CELL.2010.05.018 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 1wyn CNN2 solution structure of the ch domain of human calponin-2 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN OF HUMANTITL 2 CALPONIN-2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3oln UHRF2 crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf2 2.3Å AUTH J.R.WALKER,S.XUE,G.V.AVVAKUMOV,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE SET AND RING ASSOCIATED (SRA) DOMAIN OF HUMANTITL 2 UBIQUITIN-LIKE CONTAINING PHD AND RING FINGER DOMAINS 2TITL 3 (UHRF2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4hnm CTNNBL1 crystal structure of human catenin-beta-like 1 56 kda fragment 2.9Å AUTH X.HUANG,G.WANG,Y.WU,Z.DUTITL THE STRUCTURE OF FULL-LENGTH HUMAN CTNNBL1 REVEALS ATITL 2 DISTINCT MEMBER OF THE ARMADILLO-REPEAT PROTEIN FAMILY.REF ACTA CRYSTALLOGR.,SECT.D V. 69 1598 2013REFN ISSN 0907-4449PMID 23897482DOI 10.1107/S0907444913011360 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2h2m COMMD1 solution structure of the n-terminal domain of commd1 (murr1) -1.0Å AUTH M.SOMMERHALTER,Y.ZHANG,A.C.ROSENZWEIGTITL SOLUTION STRUCTURE OF THE COMMD1 N-TERMINAL DOMAIN.REF J.MOL.BIOL. V. 365 715 2007REFN ISSN 0022-2836PMID 17097678DOI 10.1016/J.JMB.2006.10.030 Variant Set Distributions Mapped Variants
General Structure Information 2d88 MICAL3 solution structure of the ch domain from human mical-3 protein -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMANTITL 2 MICAL-3 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d89 EHBP1 solution structure of the ch domain from human eh domain binding protein 1 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CH DOMAIN FROM HUMAN EHTITL 2 DOMAIN BINDING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants