Assessment of Structural Intolerance and Durability
General Structure Information 3uk6 RUVBL2 crystal structure of the tip48 (tip49b) hexamer 2.95Å AUTH M.PETUKHOV,A.DAGKESSAMANSKAJA,M.BOMMER,T.BARRETT,I.TSANEVA,AUTH 2 A.YAKIMOV,R.QUEVAL,A.SHVETSOV,M.KHODORKOVSKIY,E.KAS,AUTH 3 M.GRIGORIEVTITL LARGE-SCALE CONFORMATIONAL FLEXIBILITY DETERMINES THETITL 2 PROPERTIES OF AAA+ TIP49 ATPASES.REF STRUCTURE V. 20 1321 2012REFN ISSN 0969-2126PMID 22748767DOI 10.1016/J.STR.2012.05.012 Variant Set Distributions Mapped Variants
General Structure Information 2xsz RUVBL1 the dodecameric human ruvbl1:ruvbl2 complex with truncated domains ii 3.0Å AUTH S.GORYNIA,T.M.BANDEIRAS,F.G.PINHO,C.E.MCVEY,C.VONRHEIN,AUTH 2 A.ROUND,D.I.SVERGUN,P.DONNER,P.M.MATIAS,M.A.CARRONDOTITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO A DODECAMERICTITL 2 MOLECULAR MACHINE – THE RUVBL1/RUVBL2 COMPLEX.REF J.STRUCT.BIOL. V. 176 279 2011REFN ISSN 1047-8477PMID 21933716DOI 10.1016/J.JSB.2011.09.001 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2qz4 SPG7 human paraplegin, aaa domain in complex with adp 2.22Å AUTH T.KARLBERG,S.VAN DEN BERG,M.HAMMARSTROM,J.SAGEMARK,AUTH 2 I.JOHANSSON,L.HOLMBERG-SCHIAVONE,H.SCHULERTITL CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF THE HUMAN AAA+TITL 2 PROTEIN PARAPLEGIN/SPG7.REF PLOS ONE V. 4 E6975 2009REFN ESSN 1932-6203PMID 19841671DOI 10.1371/JOURNAL.PONE.0006975 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3dai ATAD2 crystal structure of the bromodomain of the human atad2 1.95Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Mapped Variants
General Structure Information 3d8b FIGNL1 crystal structure of human fidgetin-like protein 1 in complex with adp 2.0Å AUTH T.KARLBERG,M.WISNIEWSKA,J.ANDERSSON,C.H.ARROWSMITH,AUTH 2 H.BERGLUND,R.D.BUSAM,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,AUTH 4 I.JOHANSSON,A.KALLAS,T.KOTENYOVA,L.LEHTIO,M.MOCHE,AUTH 5 M.E.NILSSON,P.NORDLUND,T.NYMAN,K.OLESEN,C.PERSSON,AUTH 6 J.SAGEMARK,A.G.THORSELL,L.TRESAUGUES,S.VAN DEN BERG,M.WELIN,AUTH 7 M.WIKSTROM,H.SCHULERTITL HUMAN FIDGETIN-LIKE PROTEIN 1.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants