Assessment of Structural Intolerance and Durability
General Structure Information 2ebm RWDD1 solution structure of the rwd domain of human rwd domain containing protein 1 -1.0Å AUTH M.YONEYAMA,T.TOMIZAWA,S.KOSHIBA,S.WATABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMAN RWDTITL 2 DOMAIN CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jqz SMURF2 solution structure of the c2 domain of human smurf2 -1.0Å AUTH S.WIESNER,A.A.OGUNJIMI,H.-R.WANG,D.ROTIN,F.SICHERI,AUTH 2 J.L.WRANA,J.D.FORMAN-KAYTITL AUTOINHIBITION OF THE HECT-TYPE UBIQUITIN LIGASETITL 2 SMURF2 THROUGH ITS C2 DOMAINREF CELL(CAMBRIDGE,MASS.) V. 130 651 2007REFN ISSN 0092-8674PMID 17719543DOI 10.1016/J.CELL.2007.06.050 Variant Set Distributions Mapped Variants
General Structure Information 2dnn RBM12 solution structure of rna binding domain in rna-binding protein 12 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 RNA-BINDING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dhy CUEDC1 solution structure of the cue domain in the human cue domain containing protein 1 (cuedc1) -1.0Å AUTH C.ZHAO,T.KIGAWA,M.SATO,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CUE DOMAIN IN THE HUMANTITL 2 CUE DOMAIN CONTAINING PROTEIN 1 (CUEDC1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ccg FANCL structure of an e2-e3 complex 2.4Å AUTH C.HODSON,A.PURKISS,J.A.MILES,H.WALDENTITL STRUCTURE OF THE HUMAN FANCL RING-UBE2T COMPLEX REVEALSTITL 2 DETERMINANTS OF COGNATE E3-E2 SELECTION.REF STRUCTURE V. 22 337 2014REFN ISSN 0969-2126PMID 24389026DOI 10.1016/J.STR.2013.12.004 Variant Set Distributions Mapped Variants
General Structure Information 4ccg UBE2T structure of an e2-e3 complex 2.4Å AUTH C.HODSON,A.PURKISS,J.A.MILES,H.WALDENTITL STRUCTURE OF THE HUMAN FANCL RING-UBE2T COMPLEX REVEALSTITL 2 DETERMINANTS OF COGNATE E3-E2 SELECTION.REF STRUCTURE V. 22 337 2014REFN ISSN 0969-2126PMID 24389026DOI 10.1016/J.STR.2013.12.004 Variant Set Distributions Mapped Variants
General Structure Information 3kn1 GOLPH3 crystal structure of golgi phosphoprotein 3 n-term truncation variant 2.9Å AUTH C.S.WOOD,K.R.SCHMITZ,N.J.BESSMAN,T.G.SETTY,AUTH 2 K.M.FERGUSON,C.G.BURDTITL PTDINS4P RECOGNITION BY VPS74/GOLPH3 LINKS PTDINSTITL 2 4-KINASE SIGNALING TO RETROGRADE GOLGI TRAFFICKING.REF J.CELL BIOL. V. 187 967 2009REFN ISSN 0021-9525PMID 20026658DOI 10.1083/JCB.200909063 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cqo ZCCHC17 solution structure of the s1 rna binding domain of human hypothetical protein flj11067 -1.0Å AUTH S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE S1 RNA BINDING DOMAIN OFTITL 2 HUMAN HYPOTHETICAL PROTEIN FLJ11067REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2xus BRMS1 crystal structure of the brms1 n-terminal region 1.912Å AUTH M.SPINOLA-AMILIBIA,J.RIVERA,M.ORTIZ-LOMBARDIA,A.ROMERO,AUTH 2 J.L.NEIRA,J.BRAVOTITL THE STRUCTURE OF BRMS1 NUCLEAR EXPORT SIGNAL AND SNX6TITL 2 INTERACTING REGION REVEALS A HEXAMER FORMED BY ANTIPARALLELTITL 3 COILED COILS.REF J.MOL.BIOL. V. 411 1114 2011REFN ISSN 0022-2836PMID 21777593DOI 10.1016/J.JMB.2011.07.006 Variant Set Distributions Mapped Variants
General Structure Information 2e5g TUT1 solution structure of rna binding domain in rna binding motif protein 21 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN IN RNATITL 2 BINDING MOTIF PROTEIN 21REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants