Assessment of Structural Intolerance and Durability
General Structure Information 3k2j PBRM1 crystal structure of the 3rd bromodomain of human poly-bromodomain containing protein 1 (pb1) 2.2Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,T.KEATES,A.CHAIKUAD,A.C.W.PIKE,AUTH 2 T.KROJER,R.SETHI,F.VON DELFT,C.H.ARROWSMITH,A.EDWARDS,AUTH 3 J.WEIGELT,C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF THE 3RD BROMODOMAIN OF HUMANTITL 2 POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jxx NFATC2IP nmr solution structure of ubiquitin-like domain of nfatc2ip. northeast structural genomics consortium target hr5627 -1.0Å AUTH R.S.DOHERTY,S.DHE-PAGANON,C.FARES,A.LEMAK,C.BUTLER,AUTH 2 S.SRISAILAM,M.KARRA,A.YEE,J.WEIGELT,A.M.EDWARDS,AUTH 3 C.H.ARROWSMITHTITL SOLUTION STRUCTURE OF UBIQUITIN-LIKE DOMAIN OFTITL 2 NFATC2IP.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cry KIRREL3 solution structure of the fifth ig-like domain of human kin of irre like 3 -1.0Å AUTH C.KUROSAKI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAIN OFTITL 2 HUMAN KIN OF IRRE LIKE 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3syx SPRED1 crystal structure of the wh1 domain from human sprouty-related, evh1 domain-containing protein. northeast structural genomics consortium target hr5538b. 2.45Å AUTH S.VOROBIEV,M.SU,J.SEETHARAMAN,S.SAHDEV,R.XIAO,C.CICCOSANTI,AUTH 2 R.SHASTRY,J.K.EVERETT,R.NAIR,T.B.ACTON,B.ROST,AUTH 3 G.T.MONTELIONE,L.TONG,J.F.HUNTTITL CRYSTAL STRUCTURE OF THE WH1 DOMAIN FROM HUMANTITL 2 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2uzg USP33 zf-ubp domain of vdu1 -1.0Å AUTH M.D.ALLEN,M.BYCROFTTITL THE SOLUTION STRUCTURE OF THE ZNF UBP DOMAIN OFTITL 2 USP33/VDU1.REF PROTEIN SCI. V. 16 2072 2007REFN ISSN 0961-8368PMID 17766394DOI 10.1110/PS.072967807 Variant Set Distributions Mapped Variants
General Structure Information 2l73 NOXO1 structure of the noxo1b px domain -1.0Å AUTH N.Y.DAVIS,L.C.MCPHAIL,D.A.HORITATITL STRUCTURE OF THE NOXO1B PX DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yqr KIAA0907 solution structure of the kh domain in kiaa0907 protein -1.0Å AUTH S.KADIRVEL,F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,AUTH 2 T.TARADA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE KH DOMAIN IN KIAA0907TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ztg RBBP6 solution structure of the ring finger-like domain of retinoblastoma binding protein-6 (rbbp6) -1.0Å AUTH M.A.KAPPO,E.AB,F.HASSEM,R.A.ATKINSON,A.FARO,V.MULEYA,AUTH 2 T.MULAUDZI,J.O.POOLE,J.M.MCKENZIE,M.CHIBI,J.C.MOOLMAN-SMOOK,AUTH 3 D.J.G.REES,D.J.R.PUGHTITL SOLUTION STRUCTURE OF THE RING FINGER-LIKE DOMAIN OFTITL 2 RETINOBLASTOMA BINDING PROTEIN-6 (RBBP6) SUGGESTS ITTITL 3 FUNCTIONS AS A U-BOXREF J.BIOL.CHEM. V. 287 7146 2012REFN ISSN 0021-9258PMID 22130672DOI 10.1074/JBC.M110.217059 Variant Set […]
General Structure Information 3u1k PNPT1 crystal structure of human pnpase 2.13Å AUTH C.L.LIN,Y.-T.WANG,W.-Z.YANG,Y.-Y.HSIAO,H.S.YUANTITL CRYSTAL STRUCTURE OF HUMAN POLYNUCLEOTIDE PHOSPHORYLASE:TITL 2 INSIGHTS INTO ITS DOMAIN FUNCTION IN RNA BINDING ANDTITL 3 DEGRADATIONREF NUCLEIC ACIDS RES. V. 40 4146 2012REFN ISSN 0305-1048PMID 22210891DOI 10.1093/NAR/GKR1281 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3n9u CPSF7 crystal structure of the complex between the 25 kda subunit and the 59 kda subunit (rrm domain) of human cleavage factor im 1.92Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 M.MOCHE,T.K.NIELSEN,T.NYMAN,C.PERSSON,H.SCHULER,P.SCHUTZ,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE 25 KDA SUBUNITTITL 2 AND THE […]