General Structure Information
| PDB ID | 2rje |
| HGNC Gene Label(s) | L3MBTL1 |
| Structure Name | crystal structure of l3mbtl1 in complex with h4k20me2 (residues 17- 25), orthorhombic form ii |
| Resolution | 1.86Å |
| Reference | AUTH J.MIN,A.ALLALI-HASSANI,N.NADY,C.QI,H.OUYANG,Y.LIU,AUTH 2 F.MACKENZIE,M.VEDADI,C.H.ARROWSMITHTITL L3MBTL1 RECOGNITION OF MONO- AND DIMETHYLATED HISTONES.REF NAT.STRUCT.MOL.BIOL. V. 14 1229 2007REFN ISSN 1545-9993PMID 18026117DOI 10.1038/NSMB1340 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 312 |
| Number Of SNVs | 86 |
| Number Of Permutations | 14414 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.065 |
| p-value | 0.882 |
COSMIC
| Number Of Residues | 312 |
| Number Of SNVs | 3 |
| Number Of Permutations | 161 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.333 |
| p-value | 0.294 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 86 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.301 |
| p-value | 0.384 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
