General Structure Information
| PDB ID | 3cw3 |
| HGNC Gene Label(s) | AIM1 |
| Structure Name | crystal structure of aim1g1 |
| Resolution | 1.88Å |
| Reference | AUTH P.ARAVIND,G.WISTOW,Y.SHARMA,R.SANKARANARAYANANTITL EXPLORING THE LIMITS OF SEQUENCE AND STRUCTURE IN A VARIANTTITL 2 BETAGAMMA-CRYSTALLIN DOMAIN OF THE PROTEIN ABSENT INTITL 3 MELANOMA-1 (AIM1).REF J.MOL.BIOL. V. 381 509 2008REFN ISSN 0022-2836PMID 18582473DOI 10.1016/J.JMB.2008.06.019 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 93 |
| Number Of SNVs | 28 |
| Number Of Permutations | 6978 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.228 |
| p-value | 0.504 |
COSMIC
| Number Of Residues | 93 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.376 |
| p-value | 0.558 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
