General Structure Information
| PDB ID | 2z0d |
| HGNC Gene Label(s) | ATG4B |
| Structure Name | the crystal structure of human atg4b- lc3(1-120) complex |
| Resolution | 1.9Å |
| Reference | AUTH K.SATOO,N.N.NODA,H.KUMETA,Y.FUJIOKA,N.MIZUSHIMA,AUTH 2 Y.OHSUMI,F.INAGAKITITL THE STRUCTURE OF ATG4B-LC3 COMPLEX REVEALS THETITL 2 MECHANISM OF LC3 PROCESSING AND DELIPIDATION DURINGTITL 3 AUTOPHAGY.REF EMBO J. V. 28 1341 2009REFN ISSN 0261-4189PMID 19322194DOI 10.1038/EMBOJ.2009.80 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 308 |
| Number Of SNVs | 48 |
| Number Of Permutations | 11284 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.344 |
| p-value | 0.333 |
COSMIC
| Number Of Residues | 308 |
| Number Of SNVs | 3 |
| Number Of Permutations | 77 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.381 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.317 |
| p-value | 0.265 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
