General Structure Information
| PDB ID | 3rpn |
| HGNC Gene Label(s) | GSTK1 |
| Structure Name | crystal structure of human kappa class glutathione transferase in complex with s-hexylglutathione |
| Resolution | 1.9Å |
| Reference | AUTH B.WANG,Y.PENG,T.ZHANG,J.DINGTITL CRYSTAL STRUCTURES AND KINETIC STUDIES OF HUMAN KAPPA CLASSTITL 2 GLUTATHIONE TRANSFERASE PROVIDE INSIGHTS INTO THE CATALYTICTITL 3 MECHANISM.REF BIOCHEM.J. V. 439 215 2011REFN ISSN 0264-6021PMID 21728995DOI 10.1042/BJ20110753 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 220 |
| Number Of SNVs | 57 |
| Number Of Permutations | 5731 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.214 |
| p-value | 0.057 |
COSMIC
| Number Of Residues | 220 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 57 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.275 |
| p-value | 0.629 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
