General Structure Information
| PDB ID | 2v9r |
| HGNC Gene Label(s) | ROBO1 |
| Structure Name | first and second ig domains from human robo1 (form 2) |
| Resolution | 2.0Å |
| Reference | AUTH C.MORLOT,N.M.THIELENS,R.B.RAVELLI,W.HEMRIKA,R.A.ROMIJN,AUTH 2 P.GROS,S.CUSACK,A.A.MCCARTHYTITL STRUCTURAL INSIGHTS INTO THE SLIT-ROBO COMPLEX.REF PROC.NAT.ACAD.SCI.USA V. 104 14923 2007REFN ISSN 0027-8424PMID 17848514DOI 10.1073/PNAS.0705310104 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 197 |
| Number Of SNVs | 42 |
| Number Of Permutations | 34437 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.037 |
| p-value | 0.483 |
COSMIC
| Number Of Residues | 197 |
| Number Of SNVs | 3 |
| Number Of Permutations | 236 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 42 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 39.0 |
| K Statistic | -0.287 |
| p-value | 0.483 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
