General Structure Information
| PDB ID | 3c5w |
| HGNC Gene Label(s) | PPME1 |
| Structure Name | complex between pp2a-specific methylesterase pme-1 and pp2a core enzyme |
| Resolution | 2.8Å |
| Reference | AUTH Y.XING,Z.LI,Y.CHEN,J.B.STOCK,P.D.JEFFREY,Y.SHITITL STRUCTURAL MECHANISM OF DEMETHYLATION AND INACTIVATION OFTITL 2 PROTEIN PHOSPHATASE 2A.REF CELL(CAMBRIDGE,MASS.) V. 133 154 2008REFN ISSN 0092-8674PMID 18394995DOI 10.1016/J.CELL.2008.02.041 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 294 |
| Number Of SNVs | 43 |
| Number Of Permutations | 4905 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.043 |
| p-value | 0.304 |
COSMIC
| Number Of Residues | 294 |
| Number Of SNVs | 3 |
| Number Of Permutations | 207 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.333 |
| p-value | 0.771 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
