General Structure Information
| PDB ID | 3h3s |
| HGNC Gene Label(s) | COL4A3BP |
| Structure Name | crystal structure of the cert start domain in complex with hpa-15 |
| Resolution | 1.66Å |
| Reference | AUTH N.KUDO,K.KUMAGAI,R.MATSUBARA,S.KOBAYASHI,K.HANADA,AUTH 2 S.WAKATSUKI,R.KATOTITL CRYSTAL STRUCTURES OF THE CERT START DOMAIN WITHTITL 2 INHIBITORS PROVIDE INSIGHTS INTO THE MECHANISM OFTITL 3 CERAMIDE TRANSFER.REF J.MOL.BIOL. V. 396 245 2010REFN ISSN 0022-2836PMID 20036255DOI 10.1016/J.JMB.2009.12.029 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 234 |
| Number Of SNVs | 28 |
| Number Of Permutations | 5005 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.063 |
| p-value | 0.531 |
COSMIC
| Number Of Residues | 234 |
| Number Of SNVs | 3 |
| Number Of Permutations | 45 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | 0.333 |
| p-value | 0.519 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.579 |
| p-value | 0.154 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
