General Structure Information
| PDB ID | 2xsz |
| HGNC Gene Label(s) | RUVBL1 |
| Structure Name | the dodecameric human ruvbl1:ruvbl2 complex with truncated domains ii |
| Resolution | 3.0Å |
| Reference | AUTH S.GORYNIA,T.M.BANDEIRAS,F.G.PINHO,C.E.MCVEY,C.VONRHEIN,AUTH 2 A.ROUND,D.I.SVERGUN,P.DONNER,P.M.MATIAS,M.A.CARRONDOTITL STRUCTURAL AND FUNCTIONAL INSIGHTS INTO A DODECAMERICTITL 2 MOLECULAR MACHINE – THE RUVBL1/RUVBL2 COMPLEX.REF J.STRUCT.BIOL. V. 176 279 2011REFN ISSN 1047-8477PMID 21933716DOI 10.1016/J.JSB.2011.09.001 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 311 |
| Number Of SNVs | 44 |
| Number Of Permutations | 8891 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.026 |
| p-value | 0.077 |
COSMIC
| Number Of Residues | 311 |
| Number Of SNVs | 4 |
| Number Of Permutations | 267 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.5 |
| p-value | 0.441 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 44 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.271 |
| p-value | 0.603 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
