General Structure Information
| PDB ID | 3bin |
| HGNC Gene Label(s) | EPB41L3 |
| Structure Name | structure of the dal-1 and tslc1 (372-383) complex |
| Resolution | 2.3Å |
| Reference | AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 280 |
| Number Of SNVs | 49 |
| Number Of Permutations | 9393 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.062 |
| p-value | 0.696 |
COSMIC
| Number Of Residues | 280 |
| Number Of SNVs | 5 |
| Number Of Permutations | 273 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.5 |
| p-value | 0.171 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.067 |
| p-value | 0.019 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
