2ZMV.A | TRAPPC4

General Structure Information

PDB ID	2zmv
HGNC Gene Label(s)	TRAPPC4
Structure Name	crystal structure of synbindin
Resolution	2.8Å
Reference	AUTH S.FAN,Z.WEI,H.XU,W.GONGTITL CRYSTAL STRUCTURE OF HUMAN SYNBINDIN REVEALS TWOTITL 2 CONFORMATIONS OF LONGIN DOMAINREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 378 338 2009REFN ISSN 0006-291XPMID 18466758DOI 10.1016/J.BBRC.2008.04.143

Variant Set Distributions

ExAC Variants

Number Of Residues	202
Number Of SNVs	46
Number Of Permutations	10139
Optimal Distance Threshold	11.0
K Statistic	0.113
p-value	0.666

Mapped Variants

[+] ExAC Missense Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
11:118889512		I>V	A:3	(54.44, 32.94, 8.39)
11:118889521		V>M	A:6	(51.84, 34.29, 15.39)
11:118889575		P>A	A:24	(64.86, 34.81, 6.38)
11:118889584		E>K	A:27	(64.24, 32.84, -2.32)
11:118889588		A>G	A:28	(68.71, 32.03, -4.14)
11:118889600		F>C	A:32	(78.27, 34.74, -8.39)
11:118889601		F>L	A:32	(78.27, 34.74, -8.39)
11:118889603	rs148773147	S>T	A:33	(82.82, 34.37, -11.81)
11:118889656		F>L	A:51	(70.60, 47.42, -11.45)
11:118889666		R>L	A:54	(71.33, 37.71, -14.89)
11:118889678	rs142301628	R>Q	A:58	(63.15, 37.95, -8.14)
11:118889861		A>P	A:62	(69.23, 40.37, -0.08)
11:118889877		N>S	A:67	(80.80, 31.37, 1.43)
11:118889882		M>L	A:69	(79.02, 31.42, 6.90)
11:118889888		V>M	A:71	(76.09, 37.93, 6.88)
11:118889903		T>A	A:76	(81.40, 39.36, 7.12)
11:118889942		P>S	A:89	(92.43, 40.94, -5.70)
11:118889948		N>D	A:91	(88.23, 37.07, -2.67)
11:118889954		P>S	A:93	(86.15, 32.86, -6.02)
11:118889963		I>L	A:96	(76.07, 34.71, -2.84)
11:118889976	rs145384040	R>P	A:100	(61.64, 37.28, 1.19)
11:118889979		P>L	A:101	(64.89, 41.16, 3.13)
11:118889982		R>H	A:102	(66.89, 39.69, 8.77)
11:118889985		L>R	A:103	(60.89, 42.87, 8.96)
11:118890012		A>V	A:112	(51.40, 49.61, 13.19)
11:118890017		M>V	A:114	(47.87, 49.90, 8.85)
11:118890023		H>Y	A:116	(46.39, 52.41, 16.07)
11:118890870		I>V	A:121	(38.34, 53.19, 13.10)
11:118890910	rs143492331	I>T	A:134	(38.96, 37.27, 9.03)
11:118890913		E>G	A:135	(39.41, 42.43, 9.56)
11:118890930	rs146463975	T>A	A:141	(55.71, 43.46, 1.06)
11:118890931		T>I	A:141	(55.71, 43.46, 1.06)
11:118890935		F>L	A:142	(54.53, 43.04, 4.55)
11:118890952		Q>R	A:148	(37.89, 40.43, 16.86)
11:118890955		T>I	A:149	(36.80, 37.17, 19.41)
11:118892511		I>V	A:166	(46.55, 32.28, 7.14)
11:118892518		S>F	A:168	(42.86, 27.53, 8.48)
11:118892520		L>F	A:169	(46.57, 29.24, 11.25)
11:118892527		R>Q	A:171	(39.64, 28.57, 10.86)
11:118892532		I>L	A:173	(44.98, 30.00, 16.83)
11:118892533		I>T	A:173	(44.98, 30.00, 16.83)
11:118892575		Y>C	A:187	(44.66, 33.82, 32.71)
11:118892592		I>V	A:193	(49.14, 33.39, 27.28)
11:118894032		C>R	A:195	(50.63, 27.71, 28.46)
11:118894038		L>F	A:197	(49.86, 22.56, 26.16)
11:118894041		F>L	A:198	(48.70, 28.46, 23.56)
11:118894056		K>Q	A:203	(55.08, 26.15, 18.27)
11:118894071		V>M	A:208	(50.31, 22.78, 9.15)
11:118894078		E>G	A:210	(55.22, 27.01, 7.67)