General Structure Information
| PDB ID | 3l43 |
| HGNC Gene Label(s) | DNM3 |
| Structure Name | crystal structure of the dynamin 3 gtpase domain bound with gdp |
| Resolution | 2.27Å |
| Reference | AUTH S.YANG,W.TEMPEL,Y.TONG,L.NEDYALKOVA,X.GUAN,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE DYNAMIN 3 GTPASE DOMAIN BOUND WITHTITL 2 GDPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 242 |
| Number Of SNVs | 38 |
| Number Of Permutations | 15842 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.196 |
| p-value | 0.354 |
COSMIC
| Number Of Residues | 242 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1073 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.1 |
| p-value | 0.795 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.076 |
| p-value | 0.449 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
