General Structure Information
| PDB ID | 2ch6 |
| HGNC Gene Label(s) | NAGK |
| Structure Name | crystal structure of human n-acetylglucosamine kinase in complex with adp and glucose |
| Resolution | 2.72Å |
| Reference | AUTH W.A.WEIHOFEN,M.BERGER,H.CHEN,W.SAENGER,S.HINDERLICHTITL STRUCTURES OF HUMAN N-ACETYLGLUCOSAMINE KINASE IN TWOTITL 2 COMPLEXES WITH N-ACETYLGLUCOSAMINE AND WITH ADP/GLUCOSE:TITL 3 INSIGHTS INTO SUBSTRATE SPECIFICITY AND REGULATION.REF J.MOL.BIOL. V. 364 388 2006REFN ISSN 0022-2836PMID 17010375DOI 10.1016/J.JMB.2006.08.085 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 343 |
| Number Of SNVs | 103 |
| Number Of Permutations | 54388 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.057 |
| p-value | 0.991 |
COSMIC
| Number Of Residues | 343 |
| Number Of SNVs | 5 |
| Number Of Permutations | 956 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.2 |
| p-value | 0.858 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 103 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.113 |
| p-value | 0.961 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
