General Structure Information
| PDB ID | 3u10 |
| HGNC Gene Label(s) | HCN2 |
| Structure Name | tetramerization dynamics of the c-terminus underlies isoform-specific camp-gating in hcn channels |
| Resolution | 2.3Å |
| Reference | AUTH M.LOLICATO,M.NARDINI,S.GAZZARRINI,S.MOLLER,D.BERTINETTI,AUTH 2 F.W.HERBERG,M.BOLOGNESI,H.MARTIN,M.FASOLINI,J.A.BERTRAND,AUTH 3 C.ARRIGONI,G.THIEL,A.MORONITITL TETRAMERIZATION DYNAMICS OF C-TERMINAL DOMAIN UNDERLIESTITL 2 ISOFORM-SPECIFIC CAMP GATING IN HYPERPOLARIZATION-ACTIVATEDTITL 3 CYCLIC NUCLEOTIDE-GATED CHANNELS.REF J.BIOL.CHEM. V. 286 44811 2011REFN ISSN 0021-9258PMID 22006928DOI 10.1074/JBC.M111.297606 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 202 |
| Number Of SNVs | 39 |
| Number Of Permutations | 5739 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.027 |
| p-value | 0.433 |