General Structure Information
| PDB ID | 2h1s |
| HGNC Gene Label(s) | GRHPR |
| Structure Name | crystal structure of a glyoxylate/hydroxypyruvate reductase from homo sapiens |
| Resolution | 2.45Å |
| Reference | AUTH E.BITTO,G.E.WESENBERG,G.N.PHILLIPS JR.,C.A.BINGMAN,AUTH 2 CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS (CESG)TITL CRYSTAL STRUCTURE OF A GLYOXYLATE/HYDROXYPYRUVATE REDUCTASETITL 2 FROM HOMO SAPIENSREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 316 |
| Number Of SNVs | 80 |
| Number Of Permutations | 15048 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.034 |
| p-value | 0.674 |
ClinVar
| Number Of Residues | 316 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1232 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.048 |
| p-value | 0.758 |
COSMIC
| Number Of Residues | 316 |
| Number Of SNVs | 3 |
| Number Of Permutations | 433 |
| Optimal Distance Threshold | 54.0 |
| K Statistic | 0.667 |
| p-value | 0.315 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 80 |
| Number Of ClinVar SNVs | 7 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.023 |
| p-value | 0.824 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 80 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.537 |
| p-value | 0.103 |