General Structure Information
| PDB ID | 3jtc |
| HGNC Gene Label(s) | PROCR |
| Structure Name | importance of mg2+ in the ca2+-dependent folding of the gamma- carboxyglutamic acid domains of vitamin k-dependent clotting and anticlotting proteins |
| Resolution | 1.6Å |
| Reference | AUTH K.VADIVEL,S.AGAH,A.S.MESSER,D.CASCIO,M.S.BAJAJ,AUTH 2 S.KRISHNASWAMY,C.T.ESMON,K.PADMANABHAN,S.P.BAJAJTITL STRUCTURAL AND FUNCTIONAL STUDIES OF GAMMA-CARBOXYGLUTAMICTITL 2 ACID DOMAINS OF FACTOR VIIA AND ACTIVATED PROTEIN C: ROLE OFTITL 3 MAGNESIUM AT PHYSIOLOGICAL CALCIUM.REF J.MOL.BIOL. V. 425 1961 2013REFN ISSN 0022-2836PMID 23454357DOI 10.1016/J.JMB.2013.02.017 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 172 |
| Number Of SNVs | 50 |
| Number Of Permutations | 13614 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.033 |
| p-value | 0.764 |
COSMIC
| Number Of Residues | 172 |
| Number Of SNVs | 3 |
| Number Of Permutations | 319 |
| Optimal Distance Threshold | 38.0 |
| K Statistic | 0.667 |
| p-value | 0.534 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.453 |
| p-value | 0.391 |