General Structure Information
| PDB ID | 3qnt |
| HGNC Gene Label(s) | NPC1L1 |
| Structure Name | npc1l1 (ntd) structure |
| Resolution | 2.83Å |
| Reference | AUTH H.J.KWON,M.PALNITKAR,J.DEISENHOFERTITL THE STRUCTURE OF THE NPC1L1 N-TERMINAL DOMAIN IN A CLOSEDTITL 2 CONFORMATION.REF PLOS ONE V. 6 E1872 2011REFN ESSN 1932-6203PMID 21525977DOI 10.1371/JOURNAL.PONE.0018722 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 244 |
| Number Of SNVs | 83 |
| Number Of Permutations | 14020 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.028 |
| p-value | 0.482 |
COSMIC
| Number Of Residues | 244 |
| Number Of SNVs | 6 |
| Number Of Permutations | 299 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 0.855 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 83 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.114 |
| p-value | 0.713 |