General Structure Information
| PDB ID | 3toj |
| HGNC Gene Label(s) | ASH2L |
| Structure Name | structure of the spry domain of human ash2l |
| Resolution | 2.07Å |
| Reference | AUTH Y.CHEN,F.CAO,B.WAN,Y.DOU,M.LEITITL STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L AND ITSTITL 2 INTERACTIONS WITH RBBP5 AND DPY30.REF CELL RES. V. 22 598 2012REFN ISSN 1001-0602PMID 22231628DOI 10.1038/CR.2012.9 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 196 |
| Number Of SNVs | 41 |
| Number Of Permutations | 6501 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.307 |
| p-value | 0.207 |
COSMIC
| Number Of Residues | 196 |
| Number Of SNVs | 3 |
| Number Of Permutations | 207 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.333 |
| p-value | 0.696 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.213 |
| p-value | 0.743 |