2LFE.A | HECW2

PDB ID	2lfe
HGNC Gene Label(s)	HECW2
Structure Name	solution nmr structure of n-terminal domain of human e3 ubiquitin- protein ligase hecw2, northeast structural genomics consortium (nesg) target ht6306a
Resolution	-1.0Å
Reference	AUTH A.LEMAK,A.YEE,S.HOULISTON,M.GARCIA,S.CHITAYAT,S.DHE-PAGANON,AUTH 2 G.T.MONTELIONE,C.ARROWSMITHTITL NMR SOLUTION STRUCTURE OF N-TERMINAL DOMAIN OF E3 LIGASETITL 2 HECW2REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:197297934		Q>K	A:72	(24.26, -8.69, -47.99)
2:197297912		F>S	A:79	(22.12, -0.00, -33.18)
2:197297907		D>N	A:81	(24.24, 3.88, -26.12)
2:197297898	COSM1691785	E>K	A:84	(29.41, 11.71, -21.87)
2:197297886		P>S	A:88	(26.81, 20.21, -30.53)
2:197297873		I>T	A:92	(29.74, 7.65, -35.63)
2:197208481		N>K	A:100	(48.07, 4.78, -41.85)
2:197208470	rs376126888	N>S	A:104	(43.01, 6.93, -40.82)
2:197208468		F>V	A:105	(42.14, 12.51, -43.07)
2:197208434	rs61740605	T>I	A:116	(22.64, 12.52, -31.10)
2:197208387		M>V	A:132	(38.48, -1.29, -53.69)
2:197208381	rs61752169	P>S	A:134	(39.76, -9.30, -50.78)
2:197199238		E>D	A:135	(38.20, -9.72, -46.51)
2:197199207	rs567864110	I>V	A:146	(34.89, 18.96, -26.26)
2:197199191		R>Q	A:151	(33.32, 9.36, -24.83)
2:197199185		T>M	A:153	(35.05, 1.89, -31.10)
2:197199186	rs200798997	T>S	A:153	(35.05, 1.89, -31.10)
2:197199170	rs535521195	T>I	A:158	(34.92, -8.93, -41.83)

2LFE.A | HECW2.