General Structure Information
| PDB ID | 2hak |
| HGNC Gene Label(s) | MARK1 |
| Structure Name | catalytic and ubiqutin-associated domains of mark1/par-1 |
| Resolution | 2.6Å |
| Reference | AUTH A.MARX,C.NUGOOR,J.MUELLER,S.PANNEERSELVAM,T.TIMM,AUTH 2 M.BILANG,E.MYLONAS,D.I.SVERGUN,E.-M.MANDELKOW,AUTH 3 E.MANDELKOWTITL STRUCTURAL VARIATIONS IN THE CATALYTIC ANDTITL 2 UBIQUITIN-ASSOCIATED DOMAINS OFTITL 3 MICROTUBULE-ASSOCIATED PROTEIN/MICROTUBULETITL 4 AFFINITY REGULATING KINASE (MARK) 1 AND MARK2REF J.BIOL.CHEM. V. 281 27586 2006REFN ISSN 0021-9258PMID 16803889DOI 10.1074/JBC.M604865200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 318 |
| Number Of SNVs | 48 |
| Number Of Permutations | 24694 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.264 |
| p-value | 0.072 |
COSMIC
| Number Of Residues | 318 |
| Number Of SNVs | 10 |
| Number Of Permutations | 7421 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.222 |
| p-value | 0.256 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 48 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.051 |
| p-value | 0.985 |