General Structure Information
| PDB ID | 1×86 |
| HGNC Gene Label(s) | ARHGEF12 |
| Structure Name | crystal structure of the dh/ph domains of leukemia-associated rhogef in complex with rhoa |
| Resolution | 3.22Å |
| Reference | AUTH R.KRISTELLY,G.GAO,J.J.TESMERTITL STRUCTURAL DETERMINANTS OF RHOA BINDING AND NUCLEOTIDETITL 2 EXCHANGE IN LEUKEMIA-ASSOCIATED RHO GUANINE-NUCLEOTIDETITL 3 EXCHANGE FACTOR.REF J.BIOL.CHEM. V. 279 47352 2004REFN ISSN 0021-9258PMID 15331592DOI 10.1074/JBC.M406056200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 336 |
| Number Of SNVs | 42 |
| Number Of Permutations | 11890 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.136 |
| p-value | 0.082 |