2L5Y.A | STIM2

PDB ID	2l5y
HGNC Gene Label(s)	STIM2
Structure Name	nmr structure of calcium-loaded stim2 ef-sam.
Resolution	-1.0Å
Reference	AUTH L.ZHENG,P.B.STATHOPULOS,R.SCHINDL,G.Y.LI,C.ROMANIN,M.IKURATITL AUTO-INHIBITORY ROLE OF THE EF-SAM DOMAIN OF STIM PROTEINSTITL 2 IN STORE-OPERATED CALCIUM ENTRY.REF PROC.NATL.ACAD.SCI.USA V. 108 1337 2011REFN ISSN 0027-8424PMID 21217057DOI 10.1073/PNAS.1015125108

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
4:26921159		T>I	A:62	(3.95, 0.72, 19.21)
4:26921161		E>K	A:63	(0.58, -2.65, 18.18)
4:26921177		S>N	A:68	(3.15, 1.26, 9.79)
4:26921202		H>Q	A:76	(13.05, -0.72, 2.15)
4:26959237		I>F	A:96	(7.37, -3.72, -9.08)
4:26959283		H>R	A:111	(4.41, 7.60, -11.37)
4:26959331		R>Q	A:127	(8.61, 9.67, -1.17)
4:26997018	rs143071033	E>K	A:139	(-15.12, 9.08, 2.08)
4:26997039	rs375787750	I>V	A:146	(-15.86, 0.15, -4.64)
4:26997057	rs372691474	P>A	A:152	(-18.82, -3.96, -3.81)
4:26997066		E>K	A:155	(-17.95, -1.11, 0.82)
4:26997079	rs369386905	R>I	A:159	(-17.61, 4.28, 4.99)
4:26997087	rs372734758	N>H	A:162	(-13.59, 3.49, 11.24)
4:26997099	rs140208879	T>A	A:166	(-5.86, 3.01, 8.72)
4:26997100	rs560356253	T>M	A:166	(-5.86, 3.01, 8.72)
4:27000867		E>K	A:175	(3.67, -9.92, 10.61)
4:27000871		P>H	A:176	(-0.45, -10.29, 12.44)
4:27000886	rs139037227	S>Y	A:181	(-9.51, -7.21, 13.33)
4:27000897		I>V	A:185	(-14.57, -13.78, 7.42)
4:27000906	rs373462253	R>W	A:188	(-8.50, -17.56, 2.60)
4:27000907		R>Q	A:188	(-8.50, -17.56, 2.60)
4:27000936		A>T	A:198	(-2.55, -1.95, 0.21)
4:27000942		D>N	A:200	(-0.79, -1.23, -5.12)

2L5Y.A | STIM2.