1T3G.B | IL1RAPL1

General Structure Information

PDB ID 1t3g
HGNC Gene Label(s) IL1RAPL1
Structure Name crystal structure of the toll/interleukin-1 receptor (tir) domain of human il-1rapl
Resolution 2.3Å
Reference AUTH J.A.KHAN,E.K.BRINT,L.A.J.ONEILL,L.TONGTITL CRYSTAL STRUCTURE OF THE TOLL/INTERLEUKIN-1TITL 2 RECEPTOR DOMAIN OF HUMAN IL-1RAPLREF J.BIOL.CHEM. V. 279 31664 2004REFN ISSN 0021-9258PMID 15123616DOI 10.1074/JBC.M403434200

Variant Set Distributions

ExAC Variants

Number Of Residues 146
Number Of SNVs 6
Number Of Permutations 883
Optimal Distance Threshold 9.0
K Statistic 0.0
p-value 0.922
COSMIC

Number Of Residues 146
Number Of SNVs 4
Number Of Permutations 500
Optimal Distance Threshold 8.0
K Statistic 0.167
p-value 0.636

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 6
Number Of COSMIC SNVs 5
Optimal Distance Threshold 8.0
K Statistic 0.1
p-value 1.0

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants