3MSX.B | ARHGAP20

General Structure Information

PDB ID 3msx
HGNC Gene Label(s) ARHGAP20
Structure Name crystal structure of rhoa.gdp.mgf3 in complex with gap domain of arhgap20
Resolution 1.65Å
Reference AUTH D.UTEPBERGENOV,D.R.COOPER,U.DEREWENDA,A.V.SOMLYO,AUTH 2 Z.S.DEREWENDATITL MECHANISM OF MOLECULAR SPECIFICITY OF RHOGAP DOMAINS TOWARDSTITL 2 SMALL GTPASES OF RHOA FAMILY.REF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 192
Number Of SNVs 31
Number Of Permutations 9923
Optimal Distance Threshold 8.0
K Statistic 0.039
p-value 0.55
COSMIC

Number Of Residues 192
Number Of SNVs 3
Number Of Permutations 27
Optimal Distance Threshold 15.0
K Statistic 0.333
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 31
Number Of COSMIC SNVs 3
Optimal Distance Threshold 14.0
K Statistic -0.198
p-value 1.0

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants