3C5C.C | RASL12

General Structure Information

PDB ID 3c5c
HGNC Gene Label(s) RASL12
Structure Name crystal structure of human ras-like, family 12 protein in complex with gdp
Resolution 1.85Å
Reference AUTH L.SHEN,Y.TONG,W.TEMPEL,P.LOPPNAU,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAS-LIKE, FAMILY 12TITL 2 PROTEIN IN COMPLEX WITH GDP.REF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 163
Number Of SNVs 30
Number Of Permutations 2730
Optimal Distance Threshold 14.0
K Statistic 0.23
p-value 0.854
COSMIC

Number Of Residues 163
Number Of SNVs 4
Number Of Permutations 264
Optimal Distance Threshold 8.0
K Statistic 0.167
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 30
Number Of COSMIC SNVs 4
Optimal Distance Threshold 20.0
K Statistic -0.279
p-value 0.72

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants