General Structure Information
| PDB ID | 2ydx |
| HGNC Gene Label(s) | MAT2B |
| Structure Name | crystal structure of human s-adenosylmethionine synthetase 2, beta subunit |
| Resolution | 2.8Å |
| Reference | AUTH N.SHAFQAT,J.R.C.MUNIZ,E.S.PILKA,E.PAPAGRIGORIOU,F.VON DELFT,AUTH 2 U.OPPERMANN,W.W.YUETITL INSIGHT INTO S-ADENOSYLMETHIONINE BIOSYNTHESIS FROM THETITL 2 CRYSTAL STRUCTURES OF THE HUMAN METHIONINETITL 3 ADENOSYLTRANSFERASE CATALYTIC AND REGULATORY SUBUNITS.REF BIOCHEM.J. V. 452 27 2013REFN ISSN 0264-6021PMID 23425511DOI 10.1042/BJ20121580 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 307 |
| Number Of SNVs | 56 |
| Number Of Permutations | 9826 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.075 |
| p-value | 0.048 |
COSMIC
| Number Of Residues | 307 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2106 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.3 |
| p-value | 0.222 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 56 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | -0.538 |
| p-value | 0.151 |