General Structure Information
| PDB ID | 2f57 |
| HGNC Gene Label(s) | PAK7 |
| Structure Name | crystal structure of the human p21-activated kinase 5 |
| Resolution | 1.8Å |
| Reference | AUTH J.ESWARAN,W.H.LEE,J.E.DEBRECZENI,P.FILIPPAKOPOULOS,AUTH 2 A.TURNBULL,O.FEDOROV,S.W.DEACON,J.R.PETERSON,S.KNAPPTITL CRYSTAL STRUCTURES OF THE P21-ACTIVATED KINASES PAK4, PAK5,TITL 2 AND PAK6 REVEAL CATALYTIC DOMAIN PLASTICITY OF ACTIVE GROUPTITL 3 II PAKS.REF STRUCTURE V. 15 201 2007REFN ISSN 0969-2126PMID 17292838DOI 10.1016/J.STR.2007.01.001 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 290 |
| Number Of SNVs | 56 |
| Number Of Permutations | 26728 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.26 |
| p-value | 0.411 |
COSMIC
| Number Of Residues | 290 |
| Number Of SNVs | 15 |
| Number Of Permutations | 12616 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.295 |
| p-value | 0.277 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 56 |
| Number Of COSMIC SNVs | 12 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.06 |
| p-value | 0.795 |