General Structure Information
| PDB ID | 4lnz |
| HGNC Gene Label(s) | MYO5B |
| Structure Name | crystal structure of human myosin 5b globular domain |
| Resolution | 3.11Å |
| Reference | AUTH H.VELVARSKA,D.NIESSINGTITL STRUCTURAL INSIGHTS INTO THE GLOBULAR TAILS OF THE HUMANTITL 2 TYPE V MYOSINS MYO5A, MYO5B, AND MYO5C.REF PLOS ONE V. 8 82065 2013REFN ESSN 1932-6203PMID 24339992DOI 10.1371/JOURNAL.PONE.0082065 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 353 |
| Number Of SNVs | 99 |
| Number Of Permutations | 24409 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.16 |
| p-value | 0.034 |
COSMIC
| Number Of Residues | 353 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1012 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.167 |
| p-value | 0.306 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 99 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.736 |
| p-value | 0.097 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
