General Structure Information
| PDB ID | 4dxt |
| HGNC Gene Label(s) | SUN2 |
| Structure Name | human sun2 (aa 522-717) |
| Resolution | 2.22Å |
| Reference | AUTH B.A.SOSA,A.ROTHBALLER,U.KUTAY,T.U.SCHWARTZTITL LINC COMPLEXES FORM BY BINDING OF THREE KASH PEPTIDES TOTITL 2 DOMAIN INTERFACES OF TRIMERIC SUN PROTEINS.REF CELL(CAMBRIDGE,MASS.) V. 149 1035 2012REFN ISSN 0092-8674PMID 22632968DOI 10.1016/J.CELL.2012.03.046 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 196 |
| Number Of SNVs | 50 |
| Number Of Permutations | 27796 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.052 |
| p-value | 0.396 |
COSMIC
| Number Of Residues | 196 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1331 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.167 |
| p-value | 0.915 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.511 |
| p-value | 0.592 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
