General Structure Information
| PDB ID | 2oxc |
| HGNC Gene Label(s) | DDX20 |
| Structure Name | human dead-box rna helicase ddx20, dead domain in complex with adp |
| Resolution | 1.3Å |
| Reference | AUTH T.KARLBERG,D.OGG,C.H ARROWSMITH,H.BERGLUND,AUTH 2 R.D.BUSAM,R.COLLINS,L.G.DAHLGREN,A.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,B.M.HALLBERG,AUTH 4 M.HAMMARSTROM,M.HOGBOM,I.JOHANSSON,T.KOTENYOVA,AUTH 5 L.LEHTIO,M.MOCHE,P.NORDLUND,T.NYMAN,C.PERSSON,AUTH 6 J.SAGEMARK,P.STENMARK,M.SUNDSTROM,A.G.THORSELL,AUTH 7 S.VAN DEN BERG,J.WEIGELT,L.HOLMBERG-SCHIAVONETITL HUMAN DEAD-BOX RNA HELICASE DDX20REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 205 |
| Number Of SNVs | 47 |
| Number Of Permutations | 3876 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.184 |
| p-value | 0.501 |
COSMIC
| Number Of Residues | 205 |
| Number Of SNVs | 3 |
| Number Of Permutations | 288 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.667 |
| p-value | 0.872 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.217 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
