General Structure Information
| PDB ID | 3zrh |
| HGNC Gene Label(s) | ZRANB1 |
| Structure Name | crystal structure of the lys29, lys33-linkage-specific trabid otu deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding domain (ankubd) |
| Resolution | 2.23Å |
| Reference | AUTH J.D.F.LICCHESI,J.MIESZCZANEK,T.E.T.MEVISSEN,T.J.RUTHERFORD,AUTH 2 M.AKUTSU,S.VIRDEE,F.E.OUALID,J.W.CHIN,H.OVAA,M.BIENZ,AUTH 3 D.KOMANDERTITL AN ANKYRIN-REPEAT UBIQUITIN-BINDING DOMAIN DETERMINESTITL 2 TRABIDS SPECIFICITY FOR ATYPICAL UBIQUITIN CHAINS.REF NAT.STRUCT.MOL.BIOL. V. 19 62 2011REFN ISSN 1545-9993PMID 22157957DOI 10.1038/NSMB.2169 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 428 |
| Number Of SNVs | 66 |
| Number Of Permutations | 21879 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.349 |
| p-value | 0.055 |
COSMIC
| Number Of Residues | 428 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3042 |
| Optimal Distance Threshold | 37.0 |
| K Statistic | 0.4 |
| p-value | 0.339 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 66 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 37.0 |
| K Statistic | -0.201 |
| p-value | 0.523 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
