General Structure Information
| PDB ID | 2qq8 |
| HGNC Gene Label(s) | TBC1D14 |
| Structure Name | crystal structure of the putative rabgap domain of human tbc1 domain family member 14 |
| Resolution | 2.0Å |
| Reference | AUTH Y.TONG,W.TEMPEL,S.DIMOV,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE PUTATIVE RABGAP DOMAIN OFTITL 2 HUMAN TBC1 DOMAIN FAMILY MEMBER 14.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 284 |
| Number Of SNVs | 59 |
| Number Of Permutations | 25020 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.032 |
| p-value | 0.886 |
COSMIC
| Number Of Residues | 284 |
| Number Of SNVs | 3 |
| Number Of Permutations | 162 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.667 |
| p-value | 0.189 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.591 |
| p-value | 0.199 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
