3MOP.H | IRAK4

General Structure Information

PDB ID 3mop
HGNC Gene Label(s) IRAK4
Structure Name the ternary death domain complex of myd88, irak4, and irak2
Resolution 3.4Å
Reference AUTH S.C.LIN,Y.C.LO,H.WUTITL HELICAL ASSEMBLY IN THE MYD88-IRAK4-IRAK2 COMPLEX INTITL 2 TLR/IL-1R SIGNALLING.REF NATURE V. 465 885 2010REFN ISSN 0028-0836PMID 20485341DOI 10.1038/NATURE09121

Variant Set Distributions

ExAC Variants

Number Of Residues 103
Number Of SNVs 25
Number Of Permutations 1686
Optimal Distance Threshold 12.0
K Statistic 0.167
p-value 0.072

Mapped Variants

[+] ExAC Missense Variants