General Structure Information
| PDB ID | 3nwn |
| HGNC Gene Label(s) | KIF9 |
| Structure Name | crystal structure of the human kif9 motor domain in complex with adp |
| Resolution | 2.0Å |
| Reference | AUTH H.ZHU,W.TEMPEL,H.HE,Y.SHEN,J.WANG,G.BROTHERS,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE HUMAN KIF9 MOTOR DOMAIN IN COMPLEXTITL 2 WITH ADPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 308 |
| Number Of SNVs | 95 |
| Number Of Permutations | 28672 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.077 |
| p-value | 0.012 |
COSMIC
| Number Of Residues | 308 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 95 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 35.0 |
| K Statistic | -0.429 |
| p-value | 0.376 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
