General Structure Information
| PDB ID | 3zyi |
| HGNC Gene Label(s) | LRRC4 |
| Structure Name | netring2 in complex with ngl2 |
| Resolution | 2.6Å |
| Reference | AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNING THROUGHTITL 2 NETRING-NGL INTERACTIONSREF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 395 |
| Number Of SNVs | 71 |
| Number Of Permutations | 19198 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.111 |
| p-value | 0.135 |
COSMIC
| Number Of Residues | 395 |
| Number Of SNVs | 12 |
| Number Of Permutations | 4783 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.045 |
| p-value | 0.645 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 71 |
| Number Of COSMIC SNVs | 12 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.033 |
| p-value | 0.691 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
