General Structure Information
| PDB ID | 4fom |
| HGNC Gene Label(s) | PVRL3 |
| Structure Name | crystal structure of human nectin-3 full ectodomain (d1-d3) |
| Resolution | 3.93Å |
| Reference | AUTH O.J.HARRISON,J.VENDOME,J.BRASCH,X.JIN,S.HONG,P.S.KATSAMBA,AUTH 2 G.AHLSEN,R.B.TROYANOVSKY,S.M.TROYANOVSKY,B.HONIG,L.SHAPIROTITL NECTIN ECTODOMAIN STRUCTURES REVEAL A CANONICAL ADHESIVETITL 2 INTERFACE.REF NAT.STRUCT.MOL.BIOL. V. 19 906 2012REFN ISSN 1545-9993PMID 22902367DOI 10.1038/NSMB.2366 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 302 |
| Number Of SNVs | 61 |
| Number Of Permutations | 20863 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.09 |
| p-value | 0.658 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 39.0 |
| K Statistic | -0.502 |
| p-value | 0.093 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
