3UA9.B | TNKS2

General Structure Information

PDB ID 3ua9
HGNC Gene Label(s) TNKS2
Structure Name crystal structure of human tankyrase 2 in complex with a selective inhibitor
Resolution 2.15Å
Reference AUTH M.NARWAL,H.VENKANNAGARI,L.LEHTIOTITL STRUCTURAL BASIS OF SELECTIVE INHIBITION OF HUMANTITL 2 TANKYRASES.REF J.MED.CHEM. V. 55 1360 2012REFN ISSN 0022-2623PMID 22233320DOI 10.1021/JM201510P

Variant Set Distributions

ExAC Variants

Number Of Residues 208
Number Of SNVs 29
Number Of Permutations 10512
Optimal Distance Threshold 15.0
K Statistic 0.187
p-value 0.461

Mapped Variants

[+] ExAC Missense Variants