General Structure Information
| PDB ID | 3pq1 |
| HGNC Gene Label(s) | MTPAP |
| Structure Name | crystal structure of human mitochondrial poly(a) polymerase (papd1) |
| Resolution | 3.1Å |
| Reference | AUTH Y.BAI,S.K.SRIVASTAVA,J.H.CHANG,J.L.MANLEY,L.TONGTITL STRUCTURAL BASIS FOR DIMERIZATION AND ACTIVITY OF HUMANTITL 2 PAPD1, A NONCANONICAL POLY(A) POLYMERASE.REF MOL.CELL V. 41 311 2011REFN ISSN 1097-2765PMID 21292163DOI 10.1016/J.MOLCEL.2011.01.013 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 315 |
| Number Of SNVs | 54 |
| Number Of Permutations | 16868 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.224 |
| p-value | 0.287 |
COSMIC
| Number Of Residues | 315 |
| Number Of SNVs | 3 |
| Number Of Permutations | 262 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.581 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 54 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.282 |
| p-value | 0.884 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
