General Structure Information
| PDB ID | 2yhf |
| HGNC Gene Label(s) | CLEC5A |
| Structure Name | 1.9 angstrom crystal structure of clec5a |
| Resolution | 1.9Å |
| Reference | AUTH A.A.WATSON,A.A.LEBEDEV,B.A.HALL,A.E.FENTON-MAY,AUTH 2 A.A.VAGIN,W.DEJNIRATTISAI,J.FELCE,J.MONGKOLSAPAYA,AUTH 3 A.S.PALMA,Y.LIU,T.FEIZI,G.R.SCREATON,G.N.MURSHUDOV,AUTH 4 C.A.OCALLAGHANTITL STRUCTURAL FLEXIBILITY OF THE MACROPHAGE DENGUETITL 2 VIRUS RECEPTOR CLEC5A: IMPLICATIONS FOR LIGANDTITL 3 BINDING AND SIGNALING.REF J.BIOL.CHEM. V. 286 24208 2011REFN ISSN 0021-9258PMID 21566123DOI 10.1074/JBC.M111.226142 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 118 |
| Number Of SNVs | 32 |
| Number Of Permutations | 3196 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.073 |
| p-value | 0.867 |
COSMIC
| Number Of Residues | 118 |
| Number Of SNVs | 6 |
| Number Of Permutations | 168 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.067 |
| p-value | 0.744 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.064 |
| p-value | 0.753 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
