General Structure Information
| PDB ID | 2xsw |
| HGNC Gene Label(s) | INPP5E |
| Structure Name | crystal structure of human inpp5e |
| Resolution | 1.9Å |
| Reference | AUTH L.TRESAUGUES,P.SCHUTZ,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 E.KOUZNETSOVA,M.MOCHE,T.NYMAN,C.PERSSON,H.SCHULER,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,M.WELIN,P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN INPP5EREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 339 |
| Number Of SNVs | 87 |
| Number Of Permutations | 41592 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.06 |
| p-value | 0.022 |
ClinVar
| Number Of Residues | 339 |
| Number Of SNVs | 10 |
| Number Of Permutations | 5471 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.0 |
| p-value | 0.492 |
COSMIC
| Number Of Residues | 339 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 0.989 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of ClinVar SNVs | 10 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.06 |
| p-value | 0.64 |
Cosmic vs. ExAC
