4E74.A | PLXNA4

General Structure Information

PDB ID 4e74
HGNC Gene Label(s) PLXNA4
Structure Name crystal structure of the rho gtpase binding domain of plexin a4a
Resolution 1.58Å
Reference AUTH X.GUAN,H.WANG,W.TEMPEL,A.DONG,Y.TONG,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF THE RHO GTPASE BINDING DOMAIN OF PLEXINTITL 2 A4AREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 18
Number Of COSMIC SNVs 4
Optimal Distance Threshold 17.0
K Statistic -0.575
p-value 0.064

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants