General Structure Information
| PDB ID | 3ega |
| HGNC Gene Label(s) | PELI2 |
| Structure Name | crystal structure of pellino2 fha domain at 1.8 angstroms resolution |
| Resolution | 1.8Å |
| Reference | AUTH C.C.LIN,Y.S.HUOH,K.R.SCHMITZ,L.E.JENSEN,K.M.FERGUSONTITL PELLINO PROTEINS CONTAIN A CRYPTIC FHA DOMAIN THAT MEDIATESTITL 2 INTERACTION WITH PHOSPHORYLATED IRAK1.REF STRUCTURE V. 16 1806 2008REFN ISSN 0969-2126PMID 19081057DOI 10.1016/J.STR.2008.09.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 214 |
| Number Of SNVs | 57 |
| Number Of Permutations | 7781 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.038 |
| p-value | 0.646 |
COSMIC
| Number Of Residues | 214 |
| Number Of SNVs | 4 |
| Number Of Permutations | 116 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.5 |
| p-value | 0.539 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 57 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.236 |
| p-value | 0.653 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
