General Structure Information
| PDB ID | 3q18 |
| HGNC Gene Label(s) | GSTO2 |
| Structure Name | human glutathione transferase o2 |
| Resolution | 1.7Å |
| Reference | AUTH H.ZHOU,J.BROCK,D.LIU,P.G.BOARD,A.J.OAKLEYTITL STRUCTURAL INSIGHTS INTO THE DEHYDROASCORBATE REDUCTASETITL 2 ACTIVITY OF HUMAN OMEGA-CLASS GLUTATHIONE TRANSFERASES.REF J.MOL.BIOL. V. 420 190 2012REFN ISSN 0022-2836PMID 22522127DOI 10.1016/J.JMB.2012.04.014 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 233 |
| Number Of SNVs | 65 |
| Number Of Permutations | 23103 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.126 |
| p-value | 0.634 |
COSMIC
| Number Of Residues | 233 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1295 |
| Optimal Distance Threshold | 42.0 |
| K Statistic | 0.667 |
| p-value | 0.111 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.501 |
| p-value | 0.031 |