General Structure Information
| PDB ID | 4l1d |
| HGNC Gene Label(s) | SCN3B |
| Structure Name | voltage-gated sodium channel beta3 subunit ig domain |
| Resolution | 2.5Å |
| Reference | AUTH S.NAMADURAI,D.BALASURIYA,R.RAJAPPA,M.WIEMHOFER,K.STOTT,AUTH 2 J.KLINGAUF,J.M.EDWARDSON,D.Y.CHIRGADZE,A.P.JACKSONTITL CRYSTAL STRUCTURE AND MOLECULAR IMAGING OF THE NAV CHANNELTITL 2 BETA 3 SUBUNIT INDICATES A TRIMERIC ASSEMBLY.REF J.BIOL.CHEM. V. 289 10797 2014REFN ISSN 0021-9258PMID 24567321DOI 10.1074/JBC.M113.527994 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 108 |
| Number Of SNVs | 26 |
| Number Of Permutations | 1723 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.098 |
| p-value | 0.814 |
COSMIC
| Number Of Residues | 108 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1299 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.429 |
| p-value | 0.003 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 26 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.286 |
| p-value | 0.268 |